Effects of Various Coronary Vasodilators on Myocardial Oxygen Consumption

Hand Grip Strength and Myocardial Oxygen Consumption Index among Coronary Artery Bypass Grafting Patients

Background: Hand grip strength (HGS) is a reliable indicator of peripheral muscle strength. Although, numerous studies have investigated the strength of hand grip; little attention has been given to coronary artery disease (CAD) patients, exploring the relationship between HGS and myocardial oxygen consumption (MVO2) index. The current study aimed to evaluate the interaction between HGS and MVO...

Comparison of the effects of increased myocardial oxygen consumption and adenosine on the coronary microvascular resistance.

The purposes of this study were to determine if coronary dilation secondary to an increase in myocardial oxygen consumption (MVO2) affects the microcirculation in a homogeneous or heterogeneous manner and to determine if comparable degrees of coronary dilation produced by increasing MVO2 or exogenous (intravenous adenosine) or endogenous (intravenous dipyridamole) adenosine have similar effects...

The Hemodynamic Effects of Drugs on Myocardial Oxygen Use

The circulatory responses to high equinalgesic doses of morphine are compared with those of pethidin. The decrease in mean arterial blood pressure in case of morphine was 28p.c., with a paralleled and identical de­crease in total peripheral resistance and no negative inotropic effects.  Pethidine decreased blood pressure 54p.c., as a result of peripheral vasodilation of 46p.c. and a sharp drop...

Effects of increased myocardial oxygen consumption on coronary reactive hyperemia in the awake dog.

This study was undertaken to determine whether coronary reactive hyperemia is coupled to myocardial metabolic activity and thus proportional to myocardial oxygen consumption or whether it is mechanically determined, resulting from direct myogenic relaxation of coronary vascular smooth muscle in response to loss of the stretch stimulus provided by arterial blood pressure. In ten unanesthetized d...

Effects of glucagon on myocardial oxygen consumption and coronary blood flow in man and in dog.